I'm having this problem now as well. I first noticed it during a live show when one of my patches in my performance went all screwy for no reason. I thought it was a fluke, but then I noticed it happened again without explanation while practicing. Then, while I was editing a performance and in the offset screen, I noticed the values changing randomly on their own (the offset screen is definitely the easiest screen to see if your knobs are acting up). Like others have reported here, I suspect it is the solder on the pots that has given up and someday soon (I'm out of warranty) I'll crack it open and look at it. In the mean time, I just make sure I use the select button next to the knobs and make sure the knobs are "off" so they can't affect a live performance. I didn't really use them anyway (at least not live, but did when setting offsets, etc in programming performances), so it's not that big of a deal for me.
However, a word of caution for everyone who transports their X in an SKB hardshell case. I don't remember if I saw this on here or another site, but someone noticed that if you load an X into an SKB hardshell case, the eggcrate foam on the lid of the case that holds the X in place goes across the keyboard in only a couple of places. One of those places is directly over the knobs. The theory is (and I believe this theory is correct) when you close the lid you are putting added pressure on the knobs (pushing down on them in a sense because of the snug fit) and when the board sits on its side in the case you are causing some shear as well. And, if the case ends up upside down the entire weight of the keyboard is resting on the knobs (granted it's pressing into soft foam but it's still putting weight on those delicate solder points). I looked carefully at my lid and noticed where the contact points were in the foam and I took a knife and recessed just that portion of the foam that covers the knobs. Now the knobs go into a cavity in the foam and the foam itself rests against the front surface of the X. This is how it should have been from the beginning.
While I can't say for certain that the SKB case is what caused my knobs to fail, I did use an SKB case on almost a weekly basis for the last two years gigging, and only about four months ago did I modify the foam to make the cavity (once I learned about the problem). I highly suggest this case mod for others if you want to help protect your delicate knobs.
-Matt